Most patients with dry eye disease use a lubricating eye drop to relieve symptoms of dryness. The relief gained from using drops can be short as the drops spill out of the eyes or drain away quickly from the eye surface. The aim of this study is to evaluate the comfort of a gel lubricant in participants with moderate dry eye disease. Once applied to the eye, the gel lubricant slowly dissolves over 60-90 minutes. In this study, eligible participants will experience 4 different sizes of gel lubricants (one gel lubricant per study day) and one commercially available ocular lubricating eye drop, Systane Ultra Hydration Preservative-Free.
About the study
This study will involve one screening visit to determine eligibility for the study. Eligible participants will attend CORE for 5 study treatment days to receive either gel lubricant or the ocular lubricating drop. After all 5 study treatment days are complete, participants will return for a final visit to exit the study.
There will be a 1-7 day gap between the study visit days
Visit 0- Screening visit to determine eligibility – 1.5 hours
Day 1: Visit 1 – Receive gel lubricant or eye drops and assessment after application – 5.5 hours
Day 2: Visit 2 – Receive gel lubricant or eye drops and assessment after application – 5.5 hours
Day 3: Visit 3 – Receive gel lubricant or eye drops and assessment after application – 5.5 hours
Day 4: Visit 4 – Receive gel lubricant or eye drops and assessment after application – 5.5 hours
Day 5: Visit 5 – Receive gel lubricant or eye drops and assessment after application – 5.5 hours
Day 6: Visit 6 – Study exit – 1.25 hours
You will also be asked to complete some home questionnaires on each study day (totaling 1 hour over the duration of the study)
Total time commitment for visits – 30.25 hours over 10-30 days
The visits will include standard clinical procedures that you might encounter when you attend an eye exam.
What are the requirements?
- You are at least 18 years of age.
- You experience symptoms of dry eyes
- You do not wear contact lenses
- You use eye drops 2-4 times per day for the past 60 days
In appreciation of your time, you will receive $20 per hour you are involved in the study (up to $625 upon completion). All study products will also be provided, and parking tokens are available for those who drive to their visits.
How to participate
If you are interested in participating, please create a volunteer profile at the link below and we will contact you with more information. If you are already a registered CORE volunteer, please email firstname.lastname@example.org and mention the study name JELLYFISH. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.