Category Archives: current non-lens wearers

OCTOPUS: Seeking non-lens wearers with & without dry eye

Dry eye disease (DED) is a common ocular condition affecting up to 75% of the population and can severely impact patient quality of life. There is a need for more specific tests to diagnosis dry eye disease. The purpose of this study is to investigate the use of an ocular thermography test that measures the surface temperature of the eye using a special camera to diagnose dry eye. It will also assess if a biomarker test that looks at chemical components and antibodies in the tear film can be used to diagnose dry eye.

Both dry eye and non-dry eye participants are being recruited as part of this study. Participants in the non-dry eye group are being invited to join a control group of people without dry eye. Participants in the non-dry eye group will be selected based on their age and biological sex to match a corresponding participant in the dry eye group.

About the study

This study involves 2 study visits, over 2 consecutive days.

  • Visit 1 – Screening and DED assessments – 2.5 hours
  • Visit 2 – Additional DED assessments and study exit – 2.0 hours

Total time commitment for visits = 4.5 hours over 2 days (use of any dry eye treatments/tear drops are not permitted on the study days)  

This study will include 2 in-clinic visits over 2 consecutive days (total = 4.5 hrs) and involve collecting the tear film from your eyes and taking pictures of your eyes with a thermal imaging camera in addition to standard optometric assessments that would occur during an eye exam (including application of an eye drop and procedures that involve something touching the eye).

Participant requirements

  • You are at least 17 years of age
  • You have not worn any contact lenses in the past 6 months
  • You are not experiencing ocular allergies
  • You are not on any allergy medications or any medicated eyedrops
  • You have had an eye exam in the past 2 years
  • Dry eye group: You have a history of DED and/or using tear drops for at least the past 3 months
  • Non-dry eye group: You have no previous history of DED and no history of using any tear drops in the past

Reimbursement

In appreciation of your time, you will receive $20 per hour you are involved in the study ($90 upon completion). Parking tokens are available for those who drive to their visits.

How to participate

If you are interested in participating, please create a volunteer profile at the link below and we will contact you with more information. If you are already a registered CORE volunteer, please email COREstudies@uwaterloo.ca and mention the study name OCTOPUS. You will be provided with all relevant study information prior to study enrollment, and you are under no obligation to participate.

All studies conducted at CORE have been reviewed and received ethics clearance through a University of Waterloo Research Ethics Board.

PROTECT: Myopia control study for nearsighted children

Research has shown that early onset of myopia, or near-sightedness, with a moderate amount at a young age, increases the risk for future high degrees of near-sightedness. The goal of myopia control treatment is to slow this progression. In this study, we will be evaluating a daily disposable contact lens designed to slow myopia progression compared with a control lens.


What would happen if you and your child took part in this study?

If you both decide to take part in this study you would attend 9 study visits at CORE over 3 years, totaling 18 hours. Your child would be fitted with either the study contact lens or a control lens and asked to wear the lenses daily for the duration of the study. In appreciation of your child’s time your child will receive $20/hour for attending study visits, up to $360 for study completion. All study products will be provided by CORE.


Would this study be a good fit for my child?

This study might be a good fit for your child if:

• Must be between 7-12 years of age

• Prescription between -0.75 and -5.00 D of spherical power with no greater than 1.00 D of astigmatism in each eye, and less than 1.00 D of difference between the prescription of 2 eyes

• No history of myopia control treatment (eyedrops, spectacles or multifocal contact lenses) or participated in previous myopia control research

• No history of wearing rigid/hard contact lenses or any orthokeratology lenses

• They agree to wear the study contact lenses for a minimum of 10 hours per day, at least 6 days per week, over the study period


Reimbursement

In appreciation of the time involved, you/your child will receive $360 upon study completion. Parking passes will be provided as required.


How to participate

To take part in the PROTECT research study, please make a volunteer profile for your child.

If you meet the study criteria, you will be provided with all relevant study information prior to study enrollment, and you are under no obligation to participate. If you would like more information about nearsightedness and myopia control, click here www.corestudies.ca/myopia

PLUM: Dry eye study with gummy bear oral supplement use

Dry eye symptoms are commonplace. Dry eye is often managed with lubricating eye drops, stopping tears from draining or by stimulating tear production. Recently, there has been a shift toward focusing on nutrition for dry eye, especially with regard to oral antioxidants for relieving dry eye symptoms. This study will investigate the effectiveness of an oral supplement in form of a gummy bear containing blueberry powder.

The study consists of 3 in-office study appointments and 2 telephone calls, totaling 4.5 hours over 4 weeks.

What are the requirements?

  • You are at least 18 years of age.
  • You have dry eyes
  • You have not worn any contact lenses in the past 3 months
  • You have not used an oral supplement containing antioxidants in the past 3 months

Reimbursement

In appreciation of your time, you will receive $20 per hour you are involved in the study (up to $90). All study products will also be provided, and parking tokens are available for those who drive to their visits.

How to participate

If you are interested in participating, please email corestudies@uwaterloo.ca with the subject line “PLUM” or call 519-888-4742 for more information. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.