Category Archives: current non-lens wearers

Dry Eye Study (Study ID: PLUM)

Dry eye symptoms are commonplace. Dry eye is often managed with lubricating eye drops, stopping tears from draining or by stimulating tear production. Recently, there has been a shift toward focusing on nutrition for dry eye, especially with regard to oral antioxidants for relieving dry eye symptoms. This study will investigate the effectiveness of an oral supplement in form of a gummy bear containing blueberry powder.

The study consists of 3 in-office study appointments and 2 telephone calls, totaling 4.5 hours over 4 weeks.

What are the requirements?

  • You are at least 18 years of age.
  • You have dry eyes
  • You have not worn any contact lenses in the past 3 months
  • You have not used an oral supplement containing antioxidants in the past 3 months

Reimbursement

In appreciation of your time, you will receive $20 per hour you are involved in the study (up to $90). All study products will also be provided, and parking tokens are available for those who drive to their visits.

How to participate

If you are interested in participating, please email corestudies@uwaterloo.ca with the subject line “PLUM” or call 519-888-4742 for more information. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.

Recruiting for a new children’s myopia control study: MAP

What are we trying to learn?

Nearsightedness or “myopia” makes it difficult to see distant objects clearly and requires the use of glasses or contact lenses to achieve good vision. Typically the severity of this myopia increases as children grow, which may increase their risk of vision threatening conditions, such as glaucoma, retinal detachment and blindness later in life. A recent clinical trial of a specially designed contact lenses, called MiSight®, showed significant slowing of myopia progression in children aged 8-12. The MiSight® lens is now commercially available in Canada.

The purpose of this study is to investigate if a new design of these MiSight® soft contact lenses could provide a greater treatment effect, particularly for children whose myopia progresses quickly.

About the study

This study consists of two parts. In Part 1 (the first year), all children will wear the MiSight® myopia control lens, which has been approved for commercial use in Canada. In Part 2 (the final two years), your child will wear one of three lens types, all of which are designed to slow myopia progression. One of these three lens types is MiSight®, the other two lenses are not commercially available but have been approved by Health Canada to be assessed in this study.

At the beginning of study, you child will be randomly assigned to the type of lenses they will wear during Part 2 of the study.

Part 1

  • Visit 1a &1b (both visits normally combined): Baseline measurements (3.5 hours) and trial lens fit, dispensing Part 1 lenses (1.5 hours) – total time 5 hours
  • Visit 2: 2-week follow up – 2 hours
  • Visit 3: 3-month follow up – 1.50 hour
  • Visit 4: 6-month follow up –1.75 hours
  • Visit 5: 12-month follow up & dispense Part 2 lenses – 3.75 hours

Part 2

  • Visit 6: 2-week follow up – 1.75 hour
  • Visit 7: 6-month follow up – 2 hours
  • Visit 8: 12-month follow up – 3.75 hours
  • Visit 9: 18-month follow up – 2 hours
  • Visit 10: 24-month follow up and study exit – 3.75 hours


Total time commitment
10 visits for a total of 27.25 hours over 3 years

The visits will include standard clinical procedures that you might encounter when you attend an eye exam.

What are the requirements?

  • Children aged 7-11
  • No previous experience with myopia control treatments
  • Prescription range between -0.50 and -4.50 D
  • Willing to wear daily disposable contact lenses 10 hours/day, 6 days/week

Reimbursement

In appreciation of your time, you will receive $545 upon study completion. Parking tokens will be provided as needed.  

 How to participate

If you are interested in participating, or would like to book your first appointment, please contact CORE at 519-888-4742 or email COREstudies@uwaterloo.ca for more information.

Please provide the study ID “MAP when you call/email. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.

Safety during COVID-19

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic, including enhanced cleaning and mandatory wearing of masks by everyone. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in the “Information Letter: COVID-19 Risks for In-Person Research Study Visits” which we will ask you to sign in the event your child participates.

Research Study for Near-sighted Children: HONEYDEW

Nearsightedness can increase as children grow and the goal of myopia control is to slow down this progression. This study is comparing an investigational daily disposable contact lens designed to control myopia progression to a regular contact lens.

What would happen if you and your child took part in this study?

If you both decide to take part in this study you would attend 11 study visits at CORE over 3 years, totaling 30.5 hours. Your child would be fitted with either the study contact lens or a control lens and asked to wear the lenses daily for the duration of the study. In appreciation of your time you will receive $20/hour for attending study visits, up to $650 for study completion. All study products will be provided by CORE.

Would this study be a good fit for my child?

This study might be a good fit for your child if

  • They are between 7-12 years of age
  • They have a prescription between -0.75 and -4.50 Dioptre of spherical power with no greater than 1 Dioptre of astigmatism in each eye
  • They have never had myopia control treatment before or participated in a previous myopia control study

Safety during COVID-19

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in an information letter, which we will send to you should you express interest in participating.

To take part in the HONEYDEW research study please make a volunteer profile for your child. If you meet the study criteria, you will be provided with all relevant study information prior to study enrollment, and you are under no obligation to participate. If you would like more information about nearsightedness and myopia control click here.

New myopia study (Study ID: ASH)

In this study we are assessing how the eyes focus through a novel spectacle lens designed that slow down the progression of myopia (near-sightedness). We want to evaluate how eyes focus with these new lenses, and with two other lenses for comparison. Each pair of spectacles will be worn for approximately 20 minutes each, one after the other at a single study visit.

About the study

This study is completed in a single visit. If you/your child is found eligible to continue to the measurement session, you/they will be asked to wear each of the 3 pairs of spectacles for 15-20 minutes each, one after the other. Following 5 minutes adaptation to each pair, some focus measurements will be made.

•             Screening to determine eligibility                 0.50 hours

•             Study spectacle wear & measurements       1.25 hours

                         *Total time commitment –   1.75 hours

The study visit includes standard procedures that would often be encountered during a regular eye exam. No eye drops are used, the equipment does not touch the eyes or use bright lights.

What are the requirements?

To be eligible for this study, you must meet the following criteria:

•             Aged 6-18, inclusive

•             Currently either wear or require spectacle of low prescription (no more than -0.75 each eye) or are a current contact lens wearer (any nearsighted prescription)

Reimbursement

In appreciation of the time involved, you/your child will receive $40 upon study completion. Parking passes will be provided as required.

How to participate

If you/your child are interested in participating, please email corestudies@uwaterloo.ca with the subject line “ASH.” You will be provided with all relevant study information prior to study enrollment, and you/your child are under no obligation to participate.

Safety during COVID-19  

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic, including enhanced cleaning and mandatory wearing of masks by everyone. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in the “Information Letter: COVID-19 Risks for In-Person Research Study Visits” which we will ask you to sign in the event you participate.

Please note that you/your child will be within 2m (6 feet) of the researcher during some or most of the study visit time.  At all times, the furthest possible distance will be maintained.