Category Archives: current contact lens wearers

New contact lens study for young adults (Study ID: MULBERRY)

Despite improvements in contact lens materials, many contact lens wearers commonly report symptoms such as discomfort by the end of the day. It has been suggested that daily disposable Myopia, or nearsightedness, occurs when the eye is too long and typically worsens as children and young adults grow. The goal of myopia control treatment is to slow this progression, reducing the risk of vision threatening problems later in life. One example of myopia control is the MiSight contact lens, which has been shown by previous research to reduce myopia progression in children aged 8-12. Since some individuals see myopia progression up to age 25, this study is investigating if individuals aged 17-25 can achieve comfort and vision satisfaction with the MiSight lens.

About the study

This study consists of 4 in-office appointments and 1 at home remote questionnaire, over 3 months.

Visit 1 & 2: Screening, baseline measurements and dispense of study lenses – 1.5 hours

Visit 3: 2 week follow up – 1 hour

Visit 4: 1 month follow up – 1.25 hours

Visit 5: 2 month follow up, remote at home questionnaire – 0.25 hours

Visit 6: 3 month follow up and study exit – 1.5 hour

Total time commitment5.5 hours

The study visit includes standard procedures that would often be encountered during a regular eye exam. Please note that physical distancing cannot be guaranteed during all procedures but will be maintained whenever possible.

What are the requirements?

To be eligible for this study, you must meet the following criteria:

•             Aged 17-25

•             Currently wearing soft contact lenses

•             Prescription between -0.75 and -6.00 D, with no more than -0.75 D of astigmatism in each eye

Reimbursement

In appreciation of the time involved, you will receive $20 per hour, or $110 upon study completion. Parking passes will be provided as required.

How to participate

If you are interested in participating, please email corestudies@uwaterloo.ca with the subject line “MULBERRY”. You will be provided with all relevant study information prior to study enrollment, and you are under no obligation to participate.

Recruiting for a new contact lens study! Study code: COLLIE

What are we trying to learn?

Xiidra (lifitegrast 5.0% ophthalmic solution) is a Health Canada approved eye drop that has been shown to be effective in relieving dryness symptoms in individuals with dry eye disease. The purpose of this study is to evaluate changes in comfort and dryness in contact lens wearers after using Xiidra for 12 weeks.

About the study

If eligible, you will be asked to follow the study instructions and attend the following visits.

• Visit 1 – Screening to determine eligibility – 0.75 hour
• Visit 2 – Baseline measurements and dispense eye drops – 1 hour
• Visit 3 – 2-week follow-up visit– 1 hour
• Visit 4 – 6-week follow-up visit– 1 hour
• Visit 5 – 12-week follow-up visit– 1 hour
Total time commitment – 4.75 hours
The visits will include standard clinical procedures that you might encounter when you attend an eye exam.

What are the requirements?

• You are 18 years or older
• You have worn soft contact lenses for a minimum of 5 days/week for 6 hours/day over the past month (and are willing to continue to do so)
• You experience discomfort (e.g. dryness) when wearing your contact lenses

Reimbursement

In appreciation of your time you will receive $95 upon study completion. Parking passes will be provided as required.

How to participate

If you are interested in participating, please complete and return the attached questionnaire to corestudies@uwaterloo.ca and write the study ID, “COLLIE”, as the email title. If you have questions or would like more details, please call 519-888-4742. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.

Safety during COVID-19

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic, including enhanced cleaning and mandatory wearing of masks by everyone. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in the attached “Information Letter: COVID-19 Risks for In-Person Research Study Visits” which we will ask you to sign in the event you participate. Please note that you will be within 2m (6 feet) of the researcher during some or most of the study visit time. At all times, the furthest possible distance will be maintained. Please note, if you are aged 60 and above, you are considered at a greater risk for severe illness from the COVID-19 virus.

Recruiting for a new children’s myopia control study: MAP

What are we trying to learn?

Nearsightedness or “myopia” makes it difficult to see distant objects clearly and requires the use of glasses or contact lenses to achieve good vision. Typically the severity of this myopia increases as children grow, which may increase their risk of vision threatening conditions, such as glaucoma, retinal detachment and blindness later in life. A recent clinical trial of a specially designed contact lenses, called MiSight®, showed significant slowing of myopia progression in children aged 8-12. The MiSight® lens is now commercially available in Canada.

The purpose of this study is to investigate if a new design of these MiSight® soft contact lenses could provide a greater treatment effect, particularly for children whose myopia progresses quickly.

About the study

This study consists of two parts. In Part 1 (the first year), all children will wear the MiSight® myopia control lens, which has been approved for commercial use in Canada. In Part 2 (the final two years), your child will wear one of three lens types, all of which are designed to slow myopia progression. One of these three lens types is MiSight®, the other two lenses are not commercially available but have been approved by Health Canada to be assessed in this study.

At the beginning of study, you child will be randomly assigned to the type of lenses they will wear during Part 2 of the study.

Part 1

  • Visit 1a &1b (both visits normally combined): Baseline measurements (3.5 hours) and trial lens fit, dispensing Part 1 lenses (1.5 hours) – total time 5 hours
  • Visit 2: 2-week follow up – 2 hours
  • Visit 3: 3-month follow up – 1.50 hour
  • Visit 4: 6-month follow up –1.75 hours
  • Visit 5: 12-month follow up & dispense Part 2 lenses – 3.75 hours

Part 2

  • Visit 6: 2-week follow up – 1.75 hour
  • Visit 7: 6-month follow up – 2 hours
  • Visit 8: 12-month follow up – 3.75 hours
  • Visit 9: 18-month follow up – 2 hours
  • Visit 10: 24-month follow up and study exit – 3.75 hours


Total time commitment
10 visits for a total of 27.25 hours over 3 years

The visits will include standard clinical procedures that you might encounter when you attend an eye exam.

What are the requirements?

  • Children aged 7-11
  • No previous experience with myopia control treatments
  • Prescription range between -0.50 and -4.50 D
  • Willing to wear daily disposable contact lenses 10 hours/day, 6 days/week

Reimbursement

In appreciation of your time, you will receive $545 upon study completion. Parking tokens will be provided as needed.  

 How to participate

If you are interested in participating, or would like to book your first appointment, please contact CORE at 519-888-4742 or email COREstudies@uwaterloo.ca for more information.

Please provide the study ID “MAP when you call/email. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.

Safety during COVID-19

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic, including enhanced cleaning and mandatory wearing of masks by everyone. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in the “Information Letter: COVID-19 Risks for In-Person Research Study Visits” which we will ask you to sign in the event your child participates.

Research Study for Near-sighted Children: HONEYDEW

Nearsightedness can increase as children grow and the goal of myopia control is to slow down this progression. This study is comparing an investigational daily disposable contact lens designed to control myopia progression to a regular contact lens.

What would happen if you and your child took part in this study?

If you both decide to take part in this study you would attend 11 study visits at CORE over 3 years, totaling 30.5 hours. Your child would be fitted with either the study contact lens or a control lens and asked to wear the lenses daily for the duration of the study. In appreciation of your time you will receive $20/hour for attending study visits, up to $650 for study completion. All study products will be provided by CORE.

Would this study be a good fit for my child?

This study might be a good fit for your child if

  • They are between 7-12 years of age
  • They have a prescription between -0.75 and -4.50 Dioptre of spherical power with no greater than 1 Dioptre of astigmatism in each eye
  • They have never had myopia control treatment before or participated in a previous myopia control study

Safety during COVID-19

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in an information letter, which we will send to you should you express interest in participating.

To take part in the HONEYDEW research study please make a volunteer profile for your child. If you meet the study criteria, you will be provided with all relevant study information prior to study enrollment, and you are under no obligation to participate. If you would like more information about nearsightedness and myopia control click here.

New myopia study (Study ID: ASH)

In this study we are assessing how the eyes focus through a novel spectacle lens designed that slow down the progression of myopia (near-sightedness). We want to evaluate how eyes focus with these new lenses, and with two other lenses for comparison. Each pair of spectacles will be worn for approximately 20 minutes each, one after the other at a single study visit.

About the study

This study is completed in a single visit. If you/your child is found eligible to continue to the measurement session, you/they will be asked to wear each of the 3 pairs of spectacles for 15-20 minutes each, one after the other. Following 5 minutes adaptation to each pair, some focus measurements will be made.

•             Screening to determine eligibility                 0.50 hours

•             Study spectacle wear & measurements       1.25 hours

                         *Total time commitment –   1.75 hours

The study visit includes standard procedures that would often be encountered during a regular eye exam. No eye drops are used, the equipment does not touch the eyes or use bright lights.

What are the requirements?

To be eligible for this study, you must meet the following criteria:

•             Aged 6-18, inclusive

•             Currently either wear or require spectacle of low prescription (no more than -0.75 each eye) or are a current contact lens wearer (any nearsighted prescription)

Reimbursement

In appreciation of the time involved, you/your child will receive $40 upon study completion. Parking passes will be provided as required.

How to participate

If you/your child are interested in participating, please email corestudies@uwaterloo.ca with the subject line “ASH.” You will be provided with all relevant study information prior to study enrollment, and you/your child are under no obligation to participate.

Safety during COVID-19  

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic, including enhanced cleaning and mandatory wearing of masks by everyone. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in the “Information Letter: COVID-19 Risks for In-Person Research Study Visits” which we will ask you to sign in the event you participate.

Please note that you/your child will be within 2m (6 feet) of the researcher during some or most of the study visit time.  At all times, the furthest possible distance will be maintained.

New contact lens study (Study ID: CORGI)

What are we trying to learn?

The purpose of this study is to refit wearers of daily disposable contact lenses who currently experience symptoms of dry eye and discomfort during lens wear, with a different type of daily disposable contact lens.

We will evaluate the performance of your habitual lenses and the study lenses by taking measurements and asking you questions about your lens wearing experience.

About the study

If eligible, you will be asked to follow the study instructions and attend the following visits:

  • Visit 1 – Screening to determine eligibility– 1.5 hour
  • 1 week of habitual lens wear
  • Visit 2 – Baseline measurement & study lens dispense – 1 hour
  • 1 month of study lens wear
  • Visit 3 –1-month-follow-up visit & study exist – 1 hour


Total time commitment4.5 hours (3.5 hours of study visits plus 1 additional hour for at-home ratings)

The visits will include standard clinical procedures that you might encounter when you attend an eye exam.

What are the requirements?

  • You are at least 17 years of age
  • You are currently wearing daily disposable contact lenses at least 1 day a week and experience symptoms of dryness or discomfort
  • You are willing to wear daily disposable contact lenses at least 3 days a week for the duration of the study.
  • You are willing and able to follow instructions and maintain the appointment schedule

Reimbursement

In appreciation of your time you will receive up to $90. Parking passes will be provided as required.

How to participate

If you are interested in participating, please email corestudies@uwaterloo.ca with the subject line: CORGI.  You will be provided with all relevant study information prior to study enrolment and you are under no obligation to participate.