Category Archives: current contact lens wearers

PROTECT: Myopia control study for nearsighted children

Research has shown that early onset of myopia, or near-sightedness, with a moderate amount at a young age, increases the risk for future high degrees of near-sightedness. The goal of myopia control treatment is to slow this progression. In this study, we will be evaluating a daily disposable contact lens designed to slow myopia progression compared with a control lens.


What would happen if you and your child took part in this study?

If you both decide to take part in this study you would attend 9 study visits at CORE over 3 years, totaling 18 hours. Your child would be fitted with either the study contact lens or a control lens and asked to wear the lenses daily for the duration of the study. In appreciation of your child’s time your child will receive $20/hour for attending study visits, up to $360 for study completion. All study products will be provided by CORE.


Would this study be a good fit for my child?

This study might be a good fit for your child if:

• Must be between 7-12 years of age

• Prescription between -0.75 and -5.00 D of spherical power with no greater than 1.00 D of astigmatism in each eye, and less than 1.00 D of difference between the prescription of 2 eyes

• No history of myopia control treatment (eyedrops, spectacles or multifocal contact lenses) or participated in previous myopia control research

• No history of wearing rigid/hard contact lenses or any orthokeratology lenses

• They agree to wear the study contact lenses for a minimum of 10 hours per day, at least 6 days per week, over the study period


Reimbursement

In appreciation of the time involved, you/your child will receive $360 upon study completion. Parking passes will be provided as required.


How to participate

To take part in the PROTECT research study, please make a volunteer profile for your child.

If you meet the study criteria, you will be provided with all relevant study information prior to study enrollment, and you are under no obligation to participate. If you would like more information about nearsightedness and myopia control, click here www.corestudies.ca/myopia

BAGPIPES: Seeking DD hydrogel contact lens wearers

Seeking daily disposable contact lens wearers aged 17-60. Sleeping or napping in contact lenses limits the amount of oxygen reaching the eyes, making the cornea (front of the eye) swell more than it would during waking hours. In this study, we want to simulate sleeping in contact lenses by placing an eye patch over one eye that is wearing a contact lens during waking hours to measure the amount of swelling that occurs.

About the study

If eligible, you will be asked to follow the study instructions and attend the following visits:

  • Visit 1 (DAY 1) – Screening and study measurements – 2.75 hours
  • Visit 2 (DAY 2) – Baseline assessment and lens dispense – 1.25 hours
    *3 hour wait time between Visit 2 & 3 with eye patch covering one eye*
  • Visit 3 – Lens removal after 3 hr wait time and measurement taken (same day)
  • Visit 4 – Measurement taken after 0.5 hr from removal (same day)
  • Visit 5 – Measurement taken after 1 hr from removal (same day)
  • Visit 6 – Measurement taken after 2 hr from removal (same day)
  • Visit 7 – Measurement taken after 3 hr from removal then study exit (same day)
    *Visits 3-7 will take 4.5 hours

Total time commitment 11.5 hours over 2 days

The visits will include standard clinical procedures that you might encounter when you attend an eye exam.

What are the requirements?

  • To be eligible for this study, you must meet the following criteria:
  • Must be between 17-60 years of age
  • Have proof of eye examination within the last 2 years
  • Prescription between +4.00 and -8.00
  • No previous history of overnight contact lens wear
  • Have worn either spherical hydrogel or spherical silicone hydrogel contact lenses for the past 3 consecutive years with wearing daily disposable contact lenses of the same material type (hydrogel or silicone hydrogel, respectively) currently and at least in the past 6 months. 
  • Are currently not pregnant or nursing a child
  • Have NOT undergone eye surgery
  • Have a habitual contact lens wear schedule of at least 8 hrs a day, 5 days a week
  • Have a wearable pair of spectacles

Reimbursement

In appreciation of the time involved, you will receive up to $230. Parking passes will be provided as required.

Safety during COVID-19

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic, including enhanced cleaning and mandatory wearing of masks by everyone. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in an “Information Letter: COVID-19 Risks for In-Person Research Study Visits” which we will ask you to sign in the event you participate.

Please note that you will be within 2m (6 feet) of the researcher during some or most of the study visit time.  At all times, the furthest possible distance will be maintained.

Please note, if you are aged 60 and above, you are considered at a greater risk for severe illness from the COVID-19 virus.

How to participate

If you are interested in participating, please create a volunteer profile at the link below and we will contact you with more information. If you are already a registered CORE volunteer, please email corestudies@uwaterloo.ca and mention the study name BAGPIPES. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.

COLLIE: Contact lens comfort study

What are we trying to learn?

Xiidra (lifitegrast 5.0% ophthalmic solution) is a Health Canada approved eye drop that has been shown to be effective in relieving dryness symptoms in individuals with dry eye disease. The purpose of this study is to evaluate changes in comfort and dryness in contact lens wearers after using Xiidra for 12 weeks.

About the study

If eligible, you will be asked to follow the study instructions and attend the following visits.

• Visit 1 – Screening to determine eligibility – 0.75 hour
• Visit 2 – Baseline measurements and dispense eye drops – 1 hour
• Visit 3 – 2-week follow-up visit– 1 hour
• Visit 4 – 6-week follow-up visit– 1 hour
• Visit 5 – 12-week follow-up visit– 1 hour
Total time commitment – 4.75 hours
The visits will include standard clinical procedures that you might encounter when you attend an eye exam.

What are the requirements?

• You are 18 years or older
• You have worn soft contact lenses for a minimum of 5 days/week for 6 hours/day over the past month (and are willing to continue to do so)
• You experience discomfort (e.g. dryness) when wearing your contact lenses

Reimbursement

In appreciation of your time you will receive $95 upon study completion. Parking passes will be provided as required.

How to participate

If you are interested in participating, please complete and return the attached questionnaire to corestudies@uwaterloo.ca and write the study ID, “COLLIE”, as the email title. If you have questions or would like more details, please call 519-888-4742. You will be provided with all relevant study information prior to study enrollment and you are under no obligation to participate.

Safety during COVID-19

We want to let you know that we have revised several of our protocols to keep participants and researchers safe during the pandemic, including enhanced cleaning and mandatory wearing of masks by everyone. Measures we have taken to reduce the risk of exposure to COVID-19 are explained in the attached “Information Letter: COVID-19 Risks for In-Person Research Study Visits” which we will ask you to sign in the event you participate. Please note that you will be within 2m (6 feet) of the researcher during some or most of the study visit time. At all times, the furthest possible distance will be maintained. Please note, if you are aged 60 and above, you are considered at a greater risk for severe illness from the COVID-19 virus.

CORGI: Seeking contact lens wearers with dry eye symptoms

What are we trying to learn?

The purpose of this study is to refit wearers of daily disposable contact lenses who currently experience symptoms of dry eye and discomfort during lens wear, with a different type of daily disposable contact lens.

We will evaluate the performance of your habitual lenses and the study lenses by taking measurements and asking you questions about your lens wearing experience.

About the study

If eligible, you will be asked to follow the study instructions and attend the following visits:

  • Visit 1 – Screening to determine eligibility– 1.5 hour
  • 1 week of habitual lens wear
  • Visit 2 – Baseline measurement & study lens dispense – 1 hour
  • 1 month of study lens wear
  • Visit 3 –1-month-follow-up visit & study exist – 1 hour


Total time commitment4.5 hours (3.5 hours of study visits plus 1 additional hour for at-home ratings)

The visits will include standard clinical procedures that you might encounter when you attend an eye exam.

What are the requirements?

  • You are at least 17 years of age
  • You are currently wearing daily disposable contact lenses at least 1 day a week and experience symptoms of dryness or discomfort
  • You are willing to wear daily disposable contact lenses at least 3 days a week for the duration of the study.
  • You are willing and able to follow instructions and maintain the appointment schedule

Reimbursement

In appreciation of your time you will receive up to $90. Parking passes will be provided as required.

How to participate

If you are interested in participating, please email corestudies@uwaterloo.ca with the subject line: CORGI.  You will be provided with all relevant study information prior to study enrolment and you are under no obligation to participate.